Episode 4 Book Reading
Today's reading from my book, Letters to Zane, included:
Page 34, A letter dated August 18, 2006
Page 35, A letter dated August 19, 2006 thru August 21, 2006
Also, the continuation of my adventures with HG : "How debilitating HG is and My Flight Home."
Also visit my activist page:
http://my.care2.com/lokelani33
Sign my petition to encourage government funding of much needed HG research!
I am looking for women to share their HG Stories!
If you have suffered from HG and want to tell your story please email me : letterstozane@yahoo.com
Have A Happy Turkey Day!
Sorry for the not so great quality of this week's recording...still figuring out this mic!
Showing posts with label Research. Show all posts
Showing posts with label Research. Show all posts
Wednesday, November 21, 2007
Thursday, October 25, 2007
Theories, Theories everywhere...
But no cure yet for us...
Here are some theories of where HG may come from:
Here are some theories of where HG may come from:
What causes hyperemesis gravidarum remains unknown despite active research.
The more popular theories are categorized into 3 areas:
Hormonal
Elevated levels of human chorionic gonadotropin (hCG) or a component of this hormone may play a role in inducing vomiting. This hormone has been shown to be in women with hyperemesis gravidarum.
Thyrotoxicosis or hyperthyroidism is also believed to be associated with hyperemesis gravidarum. A portion of the hCG hormone, called beta-hCG, is thought to stimulate an increase in serum thyroid hormones, which are associated with hyperemesis in pregnant women. It is not known whether this is a cause or effect of hyperemesis.
Another hormone thought to be the involved is serotonin. This is a brain chemical that affects both the central nervous system and the gastrointestinal (GI) tract. These effects are believed to induce vomiting. During pregnancy, the upper GI tract may slow down and thus contribute to increased nausea and vomiting. Several studies have shown that this slowdown in the GI tract is increased in pregnant women with severe vomiting.
Gastrointestinal
Helicobacter pylori bacteria that live in the intestinal tract may cause the development of peptic ulcer disease. These bacteria are found in a greater percentage among pregnant women and greater still in those with hyperemesis gravidarum. Antibiotics are used to treat all these conditions.
Psychosocial
Although the idea is controversial, some researchers think the condition may be a woman's psychological reaction against the pregnancy and might arise from conflict within the family and her home environment. In these cases, counseling has been used.
Wednesday, October 17, 2007
HG worse with female fetus??
According to an article I read today, HG is worse when a woman is pregnant with a female fetus...
"Women carrying female fetuses admitted with hyperemesis gravidarum are associated with some well recognized markers of starvation and dehydration and hence with more severe hyperemesis gravidarum," Dr. P. C. Tan from the University of Malaya, Kuala Lumpur, told Reuters Health.
It was a small study only 166 women who were hospitalized with HG. According to their findings 60% had female babies. Also these women had severe ketonuria and high urea, however none of them required TPN.
Obviously more research is needed to find the real significance...
Especially since I had what is considered severe HG, requiring TPN, and I gave birth to a boy!
Here is the Article: http://www.medscape.com/viewarticle/537346
"Women carrying female fetuses admitted with hyperemesis gravidarum are associated with some well recognized markers of starvation and dehydration and hence with more severe hyperemesis gravidarum," Dr. P. C. Tan from the University of Malaya, Kuala Lumpur, told Reuters Health.
It was a small study only 166 women who were hospitalized with HG. According to their findings 60% had female babies. Also these women had severe ketonuria and high urea, however none of them required TPN.
Obviously more research is needed to find the real significance...
Especially since I had what is considered severe HG, requiring TPN, and I gave birth to a boy!
Here is the Article: http://www.medscape.com/viewarticle/537346
Wednesday, October 10, 2007
Research Participants Needed!
Hi Everyone!
I am participating in a study of possible genetic factors for Hyperemesis Gravidarum, I have been asked to pass the word around. They need 1000 women to participate.
If you have suffered from HG or know anyone who has please contact : Maternal-Fetal Medicine nvpstudy@usc.edu
Current 2007 Study: Genetics of Hyperemesis Gravidarum (HG)
HG Researchers need your help! This study is designed to identify individuals affected with HG, to study epidemiologic factors via an online survey, to collect DNA samples from saliva through the mail at no cost or travel for you, and to search for genes and risk factors that may be potentially associated with this condition. To be eligible, you must have suffered from HG and had treatment for your HG that includes I.V. Hydration, TPN or other form of non-oral feeding (ie nasogastric feeding), OR both, and are able to recruit a friend with at least 2 pregnancies who has NOT suffered from HG to serve as a control. If you live in the United States and are interested, please contact Marlena Schoenberg Fejzo, PhD at nvpstudy@usc.edu or 310-210-0802.
Identification of genes and risk factors that contribute to HG will lead to a better understanding of the causes of severe nausea and vomiting of pregnancy, and should be a first step toward the development of more effective treatments or a cure for this devastating disease.
More info can be found at : http://www.helpher.org/HER-Research/opportunities.php
0a. How did you hear about the study?
0b. Are you currently living in the US?
1. Did you have severe nausea and vomiting in a singleton (not twins or multiples) pregnancy?
2. Were you treated with IV and/or TPN (total parenteral nutrition) or other form of feeding tube (ie nasogastric feeding tube) in this pregnancy due to nausea and vomiting?
3. Did your HG pregnancy have an abnormal outcome such as molar pregnancy, Down Syndrome, or any other chromosomal abnormalities or malformations?
If yes, please explain.
4. Do you think you will be able to identify an unaffected friend of the same race/ethnicity (not a family member) with at least 2 pregnancies that went beyond 27 weeks to participate in the study as a control?
5. To the best of your knowledge, are any of your relatives enrolled in this study?
6. Are you between the age of 18-50?
I am participating in a study of possible genetic factors for Hyperemesis Gravidarum, I have been asked to pass the word around. They need 1000 women to participate.
If you have suffered from HG or know anyone who has please contact : Maternal-Fetal Medicine nvpstudy@usc.edu
Current 2007 Study: Genetics of Hyperemesis Gravidarum (HG)
HG Researchers need your help! This study is designed to identify individuals affected with HG, to study epidemiologic factors via an online survey, to collect DNA samples from saliva through the mail at no cost or travel for you, and to search for genes and risk factors that may be potentially associated with this condition. To be eligible, you must have suffered from HG and had treatment for your HG that includes I.V. Hydration, TPN or other form of non-oral feeding (ie nasogastric feeding), OR both, and are able to recruit a friend with at least 2 pregnancies who has NOT suffered from HG to serve as a control. If you live in the United States and are interested, please contact Marlena Schoenberg Fejzo, PhD at nvpstudy@usc.edu or 310-210-0802.
Identification of genes and risk factors that contribute to HG will lead to a better understanding of the causes of severe nausea and vomiting of pregnancy, and should be a first step toward the development of more effective treatments or a cure for this devastating disease.
More info can be found at : http://www.helpher.org/HER-Research/opportunities.php
0a. How did you hear about the study?
0b. Are you currently living in the US?
1. Did you have severe nausea and vomiting in a singleton (not twins or multiples) pregnancy?
2. Were you treated with IV and/or TPN (total parenteral nutrition) or other form of feeding tube (ie nasogastric feeding tube) in this pregnancy due to nausea and vomiting?
3. Did your HG pregnancy have an abnormal outcome such as molar pregnancy, Down Syndrome, or any other chromosomal abnormalities or malformations?
If yes, please explain.
4. Do you think you will be able to identify an unaffected friend of the same race/ethnicity (not a family member) with at least 2 pregnancies that went beyond 27 weeks to participate in the study as a control?
5. To the best of your knowledge, are any of your relatives enrolled in this study?
6. Are you between the age of 18-50?
Friday, July 13, 2007
US Pharmacist Info on HG
WOW! I found this in my travels online...
It is a page by the US Pharmacist online publication. The page is on Hyperemesis Gravidarum and it's really informative. In particular it had information on treatment and the different drugs used in HG!
You may be interested to see as well:
http://www.uspharmacist.com/oldformat.asp?url=newlook/files/feat/acf2f23.htm
It is a page by the US Pharmacist online publication. The page is on Hyperemesis Gravidarum and it's really informative. In particular it had information on treatment and the different drugs used in HG!
You may be interested to see as well:
http://www.uspharmacist.com/oldformat.asp?url=newlook/files/feat/acf2f23.htm
Wednesday, November 1, 2006
Statistics from Hospitals in England (2002-2003)
Hospitalization statistics for Hyperemesis Gravidarum: The following are statistics from various sources about hospitalizations and Hyperemesis Gravidarum:
0.166% (21,205) of hospital consultant episodes were for excessive vomiting in pregnancy in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
96% of hospital consultant episodes for excessive vomiting in pregnancy required hospital admission in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
100% of hospital consultant episodes for excessive vomiting in pregnancy were for women in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
59% of hospital consultant episodes for excessive vomiting in pregnancy required emergency hospital admission in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
2.5 days was the mean length of stay in hospitals for excessive vomiting in pregnancy in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
2 days was the median length of stay in hospitals for excessive vomiting in pregnancy in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
27 was the mean age of patients hospitalised for excessive vomiting in pregnancy in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
100% of hospital consultant episodes for excessive vomiting in pregnancy occurred in 15-59 year olds in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
0% of hospital consultant episodes for excessive vomiting in pregnancy occurred in people over 75 in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
1% of hospital consultant episodes for excessive vomiting in pregnancy were single day episodes in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
0.097% (50,967) of hospital bed days were for excessive vomiting in pregnancy in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
http://www.wrongdiagnosis.com/h/hyperemesis_gravidarum/hospital.htm
0.166% (21,205) of hospital consultant episodes were for excessive vomiting in pregnancy in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
96% of hospital consultant episodes for excessive vomiting in pregnancy required hospital admission in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
100% of hospital consultant episodes for excessive vomiting in pregnancy were for women in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
59% of hospital consultant episodes for excessive vomiting in pregnancy required emergency hospital admission in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
2.5 days was the mean length of stay in hospitals for excessive vomiting in pregnancy in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
2 days was the median length of stay in hospitals for excessive vomiting in pregnancy in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
27 was the mean age of patients hospitalised for excessive vomiting in pregnancy in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
100% of hospital consultant episodes for excessive vomiting in pregnancy occurred in 15-59 year olds in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
0% of hospital consultant episodes for excessive vomiting in pregnancy occurred in people over 75 in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
1% of hospital consultant episodes for excessive vomiting in pregnancy were single day episodes in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
0.097% (50,967) of hospital bed days were for excessive vomiting in pregnancy in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
http://www.wrongdiagnosis.com/h/hyperemesis_gravidarum/hospital.htm
Friday, October 20, 2006
Clinical Trials...
Clinical trials are being conducted to study the use of a delayed release drug for the treatment of HG.
http://clinicaltrials.gov/show/NCT00293644
To Participate you must meet certain criteria listed below:
Inclusion Criteria:
Singleton pregnancy of less than 7 weeks gestation.
Women who previously carried a full term pregnancy.
Severe NVP/HG in previous pregnancy by verbal confirmation as determined by questionnaire
Exclusion Criteria:
Women who refuse to participate in the study/sign a written concent
Women with insufficient English language skills to understand the questionnaires and assessment material
Women in her first pregnancy
Women who didn’t suffer severe NVP/HG in previous pregnancy
Gestational age beyond 7w+0d weeks of pregnancy
Multiple gestation
Women who have had previous adverse effects to “Diclectin®”
Women who take another anti-emetic medication
Pregnant women younger than 18 years.
See the link above for more detailed description of the clinical trial.
http://clinicaltrials.gov/show/NCT00293644
To Participate you must meet certain criteria listed below:
Inclusion Criteria:
Singleton pregnancy of less than 7 weeks gestation.
Women who previously carried a full term pregnancy.
Severe NVP/HG in previous pregnancy by verbal confirmation as determined by questionnaire
Exclusion Criteria:
Women who refuse to participate in the study/sign a written concent
Women with insufficient English language skills to understand the questionnaires and assessment material
Women in her first pregnancy
Women who didn’t suffer severe NVP/HG in previous pregnancy
Gestational age beyond 7w+0d weeks of pregnancy
Multiple gestation
Women who have had previous adverse effects to “Diclectin®”
Women who take another anti-emetic medication
Pregnant women younger than 18 years.
See the link above for more detailed description of the clinical trial.
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